Identification | More | [Name]
2-Naphthalenesulfonyl chloride | [CAS]
93-11-8 | [Synonyms]
2-NAPHTHALENESULFONYL CHLORIDE AKOS B022434 ART-CHEM-BB B022434 BETA-NAPHTHALENE SULFONYL CHLORIDE NAPHTHALENE-2-SULFONYL CHLORIDE NAPHTHALENE-2-SULPHONYL CHLORIDE NAPHTHALENE-BETA-SULFONYL CHLORIDE 2-Naphthalenylsulfonyl chloride 2-Naphthylsulfonyl chloride beta-Naphthalenesulfochloride b-Naphthalenesulfochloride b-Naphthalenesulfonyl chloride b-Naphthylsulfonyl chloride Naphthalene-2-sulfonic acid chloride Naphthalene-2-sulfonyl chloride (beta) 2-Naphthalenesulphonyl chloride Naphthalene-2-sulfonylchloride,99% 2-Naphthalenesulfonic acid chloride β-Naphthalenesulfonechloride | [EINECS(EC#)]
202-219-9 | [Molecular Formula]
C10H7ClO2S | [MDL Number]
MFCD00004087 | [Molecular Weight]
226.68 | [MOL File]
93-11-8.mol |
Chemical Properties | Back Directory | [Appearance]
LIGHT YELLOW TO BEIGE POWDER | [Melting point ]
74-76 °C (lit.) | [Boiling point ]
147.7 °C/0.6 mmHg (lit.) | [density ]
1.3661 (estimate) | [vapor pressure ]
0.004Pa at 25℃ | [Fp ]
200-202°C/13mm | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
soluble in Toluene | [form ]
Powder | [color ]
Light yellow to beige | [Water Solubility ]
insoluble | [Sensitive ]
Moisture Sensitive | [BRN ]
641898 | [InChIKey]
OPECTNGATDYLSS-UHFFFAOYSA-N | [CAS DataBase Reference]
93-11-8(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Naphthalenesulfonyl chloride(93-11-8) | [EPA Substance Registry System]
93-11-8(EPA Substance) |
Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [F ]
21 | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29049020 |
Hazard Information | Back Directory | [Chemical Properties]
LIGHT YELLOW TO BEIGE POWDER | [Uses]
2-Naphthalenesulfonyl chloride was employed as capping reagent for primary amine to convert histamine to a selective histamine H3-receptor antagonist. It was used for pre-column derivatization during the high-performance liquid chromatographic assay of neomycin sulfate. | [Flammability and Explosibility]
Notclassified | [Purification Methods]
Distil the chloride in a vacuum and/or recrystallise it (twice) from *benzene/pet ether (1:1 v/v). Purify it as the 1-sulfonyl chloride above. [Fierz-Davaid & Weissenbach Helv Chim Acta 3 2312 1920.] The sulfonamide has m 217o (from EtOH). [Beilstein 11 III 399, 11 IV 529.] |
|
|